This may or may not give rise to malignancy. It causes “sanguinaria associated keratosis”.
Sanguinaria: This is a variety of herbal extract found in toothpaste. Overuse of mouthwash containing more than 25% alcohol leads to the formation of greyish plaques on the buccal mucosa. Alcohol: People used to alcohol abuse alongside tobacco consumption develop severe mucosal infections. The symptoms may disappear on cessation of tobacco consumption. Tobacco chewing is even more dangerous and may lead to white patches in a buccal sulcus, commonly known as “tobacco pouch keratosis”. Most affected are the people who are used to reverse smoking. These people usually suffer from diffuse leukoplakia of the tongue, buccal mucosa, lips and in some cases, the floor of the mouth. Research studies have revealed a positive correlation between the degree of smoking and the size of the lesions seen in Leukoplakia. Tobacco: More than 80% of the Leukoplakia patients have a history of smoking. Multiple factors contribute to tongue infections. Fluid-filled blisters may form when the condition becomes very critical. Many a time, irregular white patches form on the mucosal linings, accompanied by pain, inflammation, and tenderness. These conditions often arise from dental problems or the use of protruding dentures. The patients may have plaque, tongue inflammation or blisters on their tongues. 
“Tongue infections” refer to a group of infections that occur in the tongue and the adjoining mucosa.
Clearly, the current global burden of oral diseases is quite alarming. The statistics of the World Health Organisation show that worldwide, 4,50,000 new cases of oral cancer are reported each year. But in the more advanced stages, the severity may increase and the disease may eventually progress to oral cancer. In the initial stages, the symptoms are negligible and can be reversed through proper treatment. These may arise from infections of the buccal cavity, tongue or the teeth. Oral diseases are becoming increasingly common at present.
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